Morpholine → 62924-85-0

Participants

Reaction Steps

Five (5.0) grams of 2-(4-isobutylphenyl)butyric acid (0.0027 mol) in 20 milliliters of anhydrous diethyl ether was added to a solution of 3.2 grams (0.0264 mol) of morpholine in 20 milliliters of anhydrous diethyl ether and the mixed solution was stirred for 5 minutes and placed in a refrigerator overnight, during which period a white solid precipitated. This solid was separated by filtration and dried. It had a melting point of 69°-71° C and a nitrogen content of 4.60% by weight which is in close agreement with a calculated nitrogen content of 4.56% for morpholine 2-(4-isobutylphenyl)butyrate having the empirical formula C18H29O3N.

Provenance & Evidence