HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → HCID 53865152, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | N-Benzoylaziridine | HCID 24286 | — |
| Reactant | 4-(4-Chlorophenyl)-4-hydroxypiperidine | HCID 38282 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 53865152 | HCID 53865152 | — |
Reaction Steps
A mixture of 0.74 parts of 1-(benzoyl)aziridine, 1.06 parts of 4-(4- chlorophenyl)-4-piperidinol, 5.4 parts of benzene and 0.4 parts of methanol is stirred and refluxed for 2 hours. The reaction mixture is cooled. Upon the addition of 1,1'-oxybisethane, the product is precipitated. After stirring for 15 minutes, the product is filtered off and dried, yielding 1.1 parts of N-{2-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl] ethyl} benzamide; mp. 169° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04031226 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-d90d8670890041debe661e89d7c8f139 |
| Source note | uspto-grants-1977_06 |