反应详情

Nα-t-Butoxycarbonyl-L-tryptophyl-O-benzyl-L-seryl-O-benzyl-L-tyrosyl-D-valine resin is prepared according to the procedure of Example 1 from Nα-t-butoxycarbonyl-D-valine resin, 11 g., 5 mmol, reacted successively with (1) 3.5 g., 9.4 mmol, of Nα-t-butoxycarbonyl-O-benzyl-L-tyrosine and 2 g., 9.7 mmol, of dicyclohexylcarbodiimide, (2) 3 g., 9.8 mmol, of Nα-t-butoxycarbonyl-O-benzyl-L-serine and 2 g. of dicyclohexylcarbodiimide and (3) 3 g., 9.85 mmol, of Nα-t-butoxycarbonyl-L-tryptophan and 2 g. of dicyclohexylcarbodiimide.