反应详情

The product of Stage (i) (1.5 g) was heated under reflux with dry zinc chloride (16 g) in glacial acetic acid (75 ml) for 24 h. The mixture was cooled, poured into water (200 ml), and the resulting solid filtered off and dried (0.95 g). Purification by flash chromatography (E) gave the title compound as a solid (125 mg). T.l.c. (F), Rf 0.65

1. temperatureThe mixture was cooled
2. filtrationthe resulting solid filtered off
3. customdried (0.95 g)
4. customPurification by flash chromatography (E)