HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 131730869, compound → Methyl cis(+/-)-5-(4-amino-3-methoxypiperidin-1-yl)-2-methylbenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 131730869 | HCID 131730869 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Product | Methyl cis(+/-)-5-(4-amino-3-methoxypiperidin-1-yl)-2-methylbenzoate | HCID 86648723 | — |
Reaction Steps
The same operation as in Example (160c) was performed using methyl cis(±)-5-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-2-methylbenzoate obtained in Example (172a) (39 mg, 0.09 mmol) and a 10% palladium-carbon catalyst (50 mg), to obtain the title compound. The resulting compound was used for the next reaction without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536197B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-a6e1c75de8f144e89e83d63e8c42fe88 |
| Source note | uspto-grants-2013_09 |