HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 437790Generated: October 29, 2026
Sodium Hydroxide → 4,5-Dihydro-4-oxothiopyrano[3,2-b]indole-5-acetic acid
https://huagongshe.com/reaction/437790
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl 4,5-dihydro-4-oxothiopyrano[3,2-b]indole-5-acetate | HCID 20326604 | — |
| Product | 4,5-Dihydro-4-oxothiopyrano[3,2-b]indole-5-acetic acid | HCID 20326619 | 90% |
Reaction Steps
A mixture of 6.0 g (0.021 mole) of ethyl 4,5-dihydro-4-oxothiopyrano[3,2-b]indole-5-acetate and 21 ml of 1N sodium hydroxide solution is stirred for 1/2 hour at 95° C. The clear solution is cooled, acidified and the solid filtered and recrystallized from isopropanol to give 4.9 g of product, mp 275°-278° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04032537 |
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| Source dataset | uspto-grants-1977_06 |
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| ORD ID | ord-227f75e339924f2e84b46c0cf14d8b8d |
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| Source note | uspto-grants-1977_06 |
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