HCID 21427067, compound → HCID 21427087, compound

HRID 437795Notes

Reaction equation

HRID 437795 reaction equation
[CH3:1][C:2]1([CH3:23])[CH2:7][O:6][C:5]([C:13]2[CH:18]=[CH:17][C:16]([NH2:19])=[C:15]([N+:20]([O-])=O)[CH:14]=2)([C:8]2[S:9][CH:10]=[CH:11][CH:12]=2)[O:4][CH2:3]1.[H][H]>[Ni].CO>[CH3:1][C:2]1([CH3:23])[CH2:3][O:4][C:5]([C:13]2[CH:14]=[C:15]([NH2:20])[C:16]([NH2:19])=[CH:17][CH:18]=2)([C:8]2[S:9][CH:10]=[CH:11][CH:12]=2)[O:6][CH2:7]1

Participants

5

Reactant 2

HCID 21427067HCID 21427067, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 21427087HCID 21427087, compoundYield 100%

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 887MethanolSolvent

Procedure

A mixture of 5.04 parts of 4-[5,5-dimethyl-2-(2-thienyl)-1,3-dioxan-2-yl]-2-nitrobenzenamine and 120 parts of methanol is hydrogenated at normal pressure and at room temperature with 3 parts of Raney-nickel catalyst. After the calculated amount of hydrogen is taken up, the catalyst is filtered off and the filtrate is evaporated, yielding 4.5 parts (100%) of 4-[5,5-dimethyl-2-(2-thienyl)-1,3-dioxan-2-yl]-1,2-benzenediamine; mp. 178° C.

Workup

  1. filtrationthe catalyst is filtered off
  2. customthe filtrate is evaporated

Sources & evidence

ORD record
ord-69dd0c3a82264d1a992aab7385d36f22
Source dataset
uspto-grants-1977_06
Patent number
US04032536

Reaction notes

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