3-(2-Chloroethyl)-1,3-oxazolidin-2-one → HCID 22767876, compound

HRID 437813Notes

Reaction equation

HRID 437813 reaction equation
[Cl:1][C:2]1[CH:23]=[CH:22][C:5]2[O:6][C:7]3[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][C:8]=3[CH:9]([N:11]3[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]3)[CH2:10][C:4]=2[CH:3]=1.[Cl:24][CH2:25][CH2:26][N:27]1[CH2:31][CH2:30][O:29][C:28]1=[O:32]>>[ClH:1].[ClH:24].[Cl:1][C:2]1[CH:23]=[CH:22][C:5]2[O:6][C:7]3[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][C:8]=3[CH:9]([N:11]3[CH2:16][CH2:15][N:14]([CH2:25][CH2:26][N:27]4[CH2:31][CH2:30][O:29][C:28]4=[O:32])[CH2:13][CH2:12]3)[CH2:10][C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 756333-(2-Chloroethyl)-1,3-oxazolidin-2-oneHCID 22767945HCID 22767945, compound

Product 1

HCID 22767876HCID 22767876, compound

Procedure

1-[2,8-dichloro-10,11-dihydro-dibenz[b,f]oxepin-10-yl]-piperazine is reacted with 3-(2-chloro-ethyl)-2-oxazolidinone in the manner described in Example 1, and there is obtained 3-[2-{4-[2,8-dichloro-10,11-dihydro-dibenz[b,f]oxepin-10-yl]-1-piperazinyl}-ethyl]-2-oxazolidinone dihydrochloride having a melting point of 187°-188° C. (with decomposition).

Sources & evidence

ORD record
ord-e66c42d641d14f7791c3efdf1f49cdab
Source dataset
uspto-grants-1977_06
Patent number
US04032525

Reaction notes

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