HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → 1-[2-Chloro-10,11-dihydro-dibenz[b,f]oxepin-10-yl]-4-methyl-piperazine dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | Maleate(2-) | HCID 5288227 | — |
| Reactant | 2-Chlorodibenzo[b,f]oxepin-10(11h)-one | HCID 12765115 | — |
| Reactant | 1-(2-Chlorodibenzo[b,f]oxepin-10-yl)-4-methylpiperazine | HCID 12765116 | — |
| Product | 1-[2-Chloro-10,11-dihydro-dibenz[b,f]oxepin-10-yl]-4-methyl-piperazine dihydrochloride | HCID 22767837 | — |
Reaction Steps
The 1-[2-chloro-dibenz[b,f]oxepin-10-yl]-4-methyl-piperazine having a melting point of 119°-120° C. [maleate: melting point 200°-202° C. (with decomposition)] used as the starting material can be prepared in an analogous manner to that described in Example 14 from 2-chloro-10,11-dihydro-dibenz[b,f]oxepin-10-one and 1-methyl-piperazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04032525 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-bf817c938c3c4a11be7f28302bb67e08 |
| Source note | uspto-grants-1977_06 |