Methyl cis(+/-)-5-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-2-fluorobenzoate → Methyl cis(+/-)-5-(4-amino-3-methoxypiperidin-1-yl)-2-fluorobenzoate

Participants

Reaction Steps

The same operation as in Example (160c) was performed using methyl cis(±)-5-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-2-fluorobenzoate obtained in Example (176a) (32 mg, 0.08 mmol) and a 10% palladium-carbon catalyst (50 mg), to obtain the title compound as an oily substance. The resulting compound was used for the next reaction without purification.

Provenance & Evidence