Cyclohexane → p-Toluenesulfonic acid

Participants

Reaction Steps

21.25 g of diethyl benzalimino-(p-nitrophenyloxysulfonyl)methyl phosphonate is dissolved in 200 ml Et2O and added over 15 min to a solution of 9.5 g of p-toluene sulfonic acid monohydrate in 150 ml Et2O. 60 ml of cyclohexane is then added and the mixture allowed to settle. The supernatant solvent is decanted and the residual oil is washed twice with a mixture of 2:1 ether cyclohexane. The residual oil is the p-toluene sulfonic acid salt of diethyl amino-(p-nitrophenyloxysulfonyl)-methyl phosphonate.

Provenance & Evidence