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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 437867Generated: October 25, 2026

Acetic Anhydride → 1(3H)-Isobenzofuranone, 3-[2,4-bis(dimethylamino)phenyl]-3-[4-(diethylamino)-2-methylphenyl]-

https://huagongshe.com/reaction/437867

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AnhydrideHCID 7918—
ReactantN,N-diethyl-m-toluidineHCID 66679—
Reactant2-(2,4-Bis(dimethylamino)benzoyl)benzoic acidHCID 20287212—
Product1(3H)-Isobenzofuranone, 3-[2,4-bis(dimethylamino)phenyl]-3-[4-(diethylamino)-2-methylphenyl]-HCID 23343365—

Reaction Steps

Condensation of 2-(2,4-bis(dimethylamino)benzoyl)-benzoic acid and N,N-diethyl-m-toluidine in the presence of acetic anhydride also afforded 3-(2,4-bis(dimethylamino)-phenyl-3-(2-methyl-4-(diethylamino)phenyl)phthalide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04032527
Source datasetuspto-grants-1977_06
ORD IDord-2841979b68f44a97a7bbc4f66c621fe4
Source noteuspto-grants-1977_06