HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl cis(+/-)-3-(4-{[(benzyloxy)carbonyl]amino}-3-propoxypiperidin-1-yl)benzoate → HCID 86648740, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl cis(+/-)-3-(4-{[(benzyloxy)carbonyl]amino}-3-propoxypiperidin-1-yl)benzoate | HCID 86648737 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Product | HCID 86648740 | HCID 86648740 | 81.3% |
Reaction Steps
The same operation as in Example (160c) was performed using methyl cis(±)-3-(4-{[(benzyloxy)carbonyl]amino}-3-propoxypiperidin-1-yl)benzoate obtained in Example (178a) (78 mg, 0.18 mmol) and a 10% palladium-carbon catalyst (100 mg), to obtain 42.8 mg of the title compound as a pale yellow oily substance (80%). The resulting compound was used for the next reaction without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536197B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-fc7879fc05334c4a9a6d303a10196131 |
| Source note | uspto-grants-2013_09 |