HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → 3-(1,1-Dimethoxyethyl)hept-5-yn-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | 2,2-Dimethoxypropane | HCID 6495 | — |
| Reactant | 3-(But-2-yn-1-yl)pentane-2,4-dione | HCID 20372133 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-(1,1-Dimethoxyethyl)hept-5-yn-2-one | HCID 20372132 | — |
Reaction Steps
A solution of 38.0 g. (0.25 mol.) of 3-acetyl-5-heptyn-2-one, 32.3 g. (0.31 mol.) of 2,2-dimethoxy-propane, and 5 mg. of p-toluenesulfonic acid in 25 ml. of absolute methanol and 25 ml. of benzene was slowly distilled until the material boiling below 65° had been removed, then stirred with 1 g. of sodium carbonate and filtered to produce 2,2-dimethoxy-3-acetyl-5-heptyne in the filtrate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04032577 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-776fb5b9af60495a8200cd3065b9a001 |
| Source note | uspto-grants-1977_06 |