Methylamine → N-(3-Methylaminocarbonyl-5-nitrobenzoyl)-glycine methylammonium salt

HRID 437913Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 437913
[CH3:1][NH2:2].CO[C:5]([C:7]1[CH:8]=[C:9]([CH:17]=[C:18]([N+:20]([O-:22])=[O:21])[CH:19]=1)[C:10]([NH:12][CH2:13][C:14]([OH:16])=[O:15])=[O:11])=[O:6]>CO>[CH3:10][NH3+:12].[CH3:1][NH:2][C:5]([C:7]1[CH:8]=[C:9]([CH:17]=[C:18]([N+:20]([O-:22])=[O:21])[CH:19]=1)[C:10]([NH:12][CH2:13][C:14]([O-:16])=[O:15])=[O:11])=[O:6]

Komponenten

4

Edukt 2

HCID 6329MethylamineHCID 21427264N-(3-Methoxycarbonyl-5-nitrobenzoyl)-glycine

Produkt 1

HCID 131710164N-(3-Methylaminocarbonyl-5-nitrobenzoyl)-glycine methylammonium salt

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

15 ml. of liquid methylamine is added at 0° C. to 42.3 g. (0.15 mole) of N-(3-methoxycarbonyl-5-nitrobenzoyl)-glycine (VIa) in 150 ml. of methanol; the reaction mixture is stored for 3 days at room temperature. Then, the mixture is concentrated to dryness under vacuum, and the residue is refluxed with absolute alcohol. After cooling, the reaction mixture is filtered, washed with alcohol and dried under vacuum.

Aufarbeitung

  1. concentrationThen, the mixture is concentrated to dryness under vacuum
  2. temperaturethe residue is refluxed with absolute alcohol
  3. temperatureAfter cooling
  4. filtrationthe reaction mixture is filtered
  5. washwashed with alcohol
  6. customdried under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-21880355243e450ca69f703425ae196e
Quelldatensatz
uspto-grants-1977_06
Patentnummer
US04032567

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