HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Carbonate → 1-[2-(Tetrahydro-2-oxo-1,3-oxazin-3-yl)ethyl]-3-phenylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Carbonate | HCID 7766 | — |
| Reactant | 3-Chloro-1-propanol | HCID 12313 | — |
| Reactant | N-(2-Aminoethyl)-N'-phenylurea | HCID 12681829 | — |
| Reactant | 1-[2-(3-Hydroxypropylamino)ethyl]-3-phenylurea | HCID 21427416 | — |
| Product | 1-[2-(Tetrahydro-2-oxo-1,3-oxazin-3-yl)ethyl]-3-phenylurea | HCID 21427414 | — |
Reaction Steps
When 3-chloropropanol is reacted with 1-(2-aminoethyl)-3-phenylurea and the resulting 1-[2-(3-hydroxypropylamino)ethyl]-3-phenylurea is reacted with diethyl carbonate according to the general processes of steps 1 and 2 of Example 2, there is obtained 1-[2-(tetrahydro-2-oxo-1,3-oxazin-3-yl)-ethyl]-3-phenylurea.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04032638 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-1b721f344cc94762af0d011c54ff030d |
| Source note | uspto-grants-1977_06 |