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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 43795Erstellt: 25. Oktober 2026

Methyl cis(+/-)-3-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-4-fluorobenzoate → HCID 86648746, Verbindung

https://huagongshe.com/reaction/43795

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktMethyl cis(+/-)-3-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-4-fluorobenzoateHCID 86648744—
KatalysatorHCID 178418390HCID 178418390—
ProduktHCID 86648746HCID 8664874626,6%

Reaktionsschritte

The same operation as in Example (160c) was performed using methyl cis(±)-3-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-4-fluorobenzoate obtained in Example (181a) (101 mg, 0.24 mmol) and a 10% palladium-carbon catalyst (100 mg), to obtain 18 mg of the title compound as a colorless oily substance (26%). The resulting compound was used for the next reaction without purification.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08536197B2
Quelldatensatzuspto-grants-2013_09
ORD IDord-44e0541beb45485083542b8e7c3ddcb2
Quellennotizuspto-grants-2013_09