HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloroaniline → 3-acetyl-5-[1-(4-chloroanilino)ethylidene]-4-hydroxypyran-2,6-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloroaniline | HCID 7812 | — |
| Reactant | 3,5-Diacetyl-2,6-dihydroxy-4h-pyran-4-one | HCID 135465969 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 3-acetyl-5-[1-(4-chloroanilino)ethylidene]-4-hydroxypyran-2,6-dione | HCID 178467266 | — |
Reaction Steps
3,5-Diacetyl-4,6-dihydroxy-2H-pyran-2-one (5.3 g.) is dissolved in 200 ml. of boiling toluene and an equimolar amount of p-chloroaniline is added. The mixture is refluxed for 12 hours, cooled and filtered to yield 5-acetyl-3-[1-(p-chlorophenylamino)ethylidene]-4-hydroxy-2H-pyran-2,6(3H)-dione, m.p. 205°-206° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04032652 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-33891477f837461d97e2f2397f921677 |
| Source note | uspto-grants-1977_06 |