L-Tyrosine → HCID 53897591, compound

HRID 438014Notes

Reaction equation

HRID 438014 reaction equation
O=[CH:2][C@@H:3]([C@@H:5]([C@@H:7]([CH2:9][OH:10])[OH:8])[OH:6])[OH:4].[NH2:11][C@H:12]([C:21]([OH:23])=[O:22])[CH2:13][C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][CH:15]=1>[Ni]>[OH:4][CH:3]([CH:5]([OH:6])[CH:7]([OH:8])[CH2:9][OH:10])[CH2:2][NH:11][C@H:12]([C:21]([OH:23])=[O:22])[CH2:13][C:14]1[CH:15]=[CH:16][C:17]([OH:20])=[CH:18][CH:19]=1

Participants

4

Reactant 2

HCID 6057L-TyrosineHCID 5311110Aldehydo-D-ribose

Product 1

HCID 53897591HCID 53897591, compound

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

The product was made from D-ribose and L-(-)-tyrosine using Raney nickel as a catalyst and heating for 2 hours to 50° C. and for 4 hours to 70° C. The reaction product was yellowish, wax-like mass with an RF -value of 0.65 (determined as indicated under Example M).

Workup

  1. temperatureheating for 2 hours to 50° C. and for 4 hours to 70° C

Sources & evidence

ORD record
ord-f275aafd113d4077b4a41a89d0eef14d
Source dataset
uspto-grants-1977_06
Patent number
US04032676

Reaction notes

Loading…