Benzyl Alcohol → HCID 53990429, compound

Participants

Reaction Steps

A mixture of 10.4 g (0.027 mole) of 2-(5-tetradecyloxy)thenoylacetic acid, 4.4 g (0.027 mole) of N,N'-carbonyldiimidazole, and anhydrous tetrahydrofuran is stirred until the evolution of carbon dioxide gas stops. The mixture is cooled on an ice bath, in 3.0 g (0.027 mole) of benzyl alcohol is added. The reaction is allowed to warm to room temperature and evaporated to dryness. The residue is extracted with ether-H2O. The ether layer is washed with 10% aqueous HCl, then water, then saturated sodium chloride, dried with sodium sulfate and evaporated to dryness to give 5-tetradecyloxythen-2-oylacetic acid benzyl ester.

Provenance & Evidence