Butanal → HCID 53759850, compound

Participants

Reaction Steps

A mixture of 74.1 g (0.275 mole) of tris(2-chloroethyl phosphite, 19.8 g (0.275 mole) of n-butyraldehyde, and 23.8 g (0.25 mole) of methanesulfonamide in 130 ml of chlorobenzene is stirred and warmed at 90°-110° under nitrogen for 5.5 hrs, and then the solvent and ethylenechlorohydrin by-product are removed at reduced pressure. Ether (100 ml) is added to the residue, resulting in formation of a white solid after several hours. Recrystallization from carbon tetrachloride gives 33.2 g: mp 69°-72°; 31P nmr (CDCl3)- 24.4 ppm.

Provenance & Evidence