Lithium hydroxide, monohydrate → 3-{4-[(4-Chloro-5-ethyl-1H-imidazole-2-carbonyl)amino]piperidine-1-yl}benzoic acid

Participants

Reaction Steps

The same operation as in Example (1i) was performed using methyl 3-{4-[(4-chloro-5-ethyl-1H-imidazole-2-carbonyl)amino]piperidin-1-yl}benzoate obtained in Example (192d) (87.5 mg, 0.224 mmol) and lithium hydroxide monohydrate (47 mg, 1.12 mmol), to obtain 53 mg of the title compound as a white solid (63%).

Provenance & Evidence