Sodium Carbonate → HCID 86648799, Verbindung

Beteiligte Stoffe

Reaktionsschritte

The same operation as in Example (196c) was performed using tert-butyl trans(±)-4-{[(4-chloro-5-ethyl-1H-imidazol-2-yl)carbonyl]amino}-3-(ethylamino)piperidine-1-carboxylate obtained in Example (207a) (25.0 mg, 0.063 mmol), 4 N hydrochloric acid/1,4-dioxane (1 mL), ethyl 2-bromo-4-methyl-1,3-thiazole-5-carboxylate (19 mg, 0.075 mmol) and sodium carbonate (66 mg, 0.625 mmol), to obtain 12 mg of the title compound (41%) as a colorless solid.

Herkunft & Nachweise