HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 86648817, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Ethyl 2-bromo-4-methyl-1,3-thiazole-5-carboxylate | HCID 2824057 | — |
| Reactant | HCID 86648815 | HCID 86648815 | — |
| Product | HCID 86648817 | HCID 86648817 | 76.8% |
Reaction Steps
The same operation as in Example (232c) was performed using trans(±)-3-(tert-butoxycarbonyl)amino-2-ethylazetidine obtained in Example (234e) (110 mg, 0.55 mmol), ethyl 2-bromo-4-methylthiazole-5-carboxylate (137 mg, 0.55 mmol) and diisopropylethylamine (0.19 mL, 1.10 mmol), to obtain 156 mg of the title compound as a pale yellow oily substance (77%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536197B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-ffa25b59ad4e4e13bbee12562f4ea9b0 |
| Source note | uspto-grants-2013_09 |