HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzhydrylamine → cis(+/-)-1-(Diphenylmethyl)-2-ethylazetidin-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzhydrylamine | HCID 7036 | — |
| Reactant | (2R*)-2-[(1S*)-1-bromopropyl]oxirane | HCID 86648818 | — |
| Product | cis(+/-)-1-(Diphenylmethyl)-2-ethylazetidin-3-ol | HCID 10038631 | 29% |
Reaction Steps
The same operation as in Example (234b) was performed using (2R*)-2-[(1S*)-1-bromopropyl]oxirane obtained in Example (235a) (1.50 g, 9.09 mmol) and benzhydrylamine (1.57 mL, 9.09 mmol), to obtain 699 mg of the title compound as a pale yellow solid (29%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536197B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-d3beea6e4def4d39ae80f2382e9a50cc |
| Source note | uspto-grants-2013_09 |