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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 439217Generated: October 29, 2026

2-Chloropyridine → Tert-butyl 2-pyridin-2-ylpyrrole-1-carboxylate

https://huagongshe.com/reaction/439217

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChloropyridineHCID 7977—
Reactant1-(tert-Butoxycarbonyl)-2-pyrroleboronic AcidHCID 2734321—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
CatalystHCID 178422002HCID 178422002—
SolventWaterHCID 962—
SolventTetrahydrofuranHCID 8028—
ProductTert-butyl 2-pyridin-2-ylpyrrole-1-carboxylateHCID 860582059.2%
WorkupAcetoneHCID 180—
Internal standardNaphthaleneHCID 931—
WorkupWaterHCID 962—

Reaction Conditions

Temperature69.5 °C

Provenance & Evidence

DOI10.1039/C6RE00153J
Source datasetReizman Suzuki Cross-Coupling
ORD IDord-85471d531c8e4b058057e93505b586c1
Source noteReizman Suzuki Cross-Coupling