HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 54563804, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 54448843 | HCID 54448843 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 54563804 | HCID 54563804 | 89% |
Reaction Steps
1.0g of 2-bromo-4-ethyl-thiazole-5-carboxylic acid (cyano-thiophen-2-yl-methyl)-amide, 0.40ml of triethylamine and 0.58ml of methylamine were added to 10ml of tetrahydrofuran. The reaction mixture was stirred under reflux for 4 hours and then treated according to the same procedure as EXAMPLE 10 to obtain 0.77g (Yield 89%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05514643 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-0b228e9c16a649b7b2ca49ad1123a086 |
| Source note | uspto-grants-1996_05 |