HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-methoxybenzene-1-sulfonyl chloride → 5-Bromo-2-methoxy-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-methoxybenzene-1-sulfonyl chloride | HCID 520020 | — |
| Reactant | 4-Bromo-3-methylisoxazol-5-amine | HCID 10487519 | — |
| Product | 5-Bromo-2-methoxy-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide | HCID 18617333 | 61% |
Reaction Steps
5-Bromo-2-methoxy-N-(4-bromo-3-methyl-5-isoxazolyl)benzenesulfonamide was prepared from 5-amino-4-bromo-3-methylisoxazole and 5-bromo-2-methoxybenzenesulfonyl chloride according to the procedures described in Example 5. The crude product was purified by recrystallization from ethyl acetate/hexanes to give a crystalline solid, m.p. 92°-195° C., yield 61%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05514691 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-336522347f294803992ac0284b8b5610 |
| Source note | uspto-grants-1996_05 |