Benzenesulfonyl chloride → HCID 22616246, compound

HRID 439387Notes

Reaction equation

HRID 439387 reaction equation
[NH2:1][C:2]1[C:6]([I:7])=[C:5]([CH3:8])[O:4][N:3]=1.[C:9]1([S:15](Cl)(=[O:17])=[O:16])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[I:7][C:6]1[C:2]([NH:1][S:15]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)(=[O:17])=[O:16])=[N:3][O:4][C:5]=1[CH3:8]

Participants

3

Reactant 2

HCID 7369Benzenesulfonyl chlorideHCID 186173504-Iodo-5-methyl-1,2-oxazol-3-amine

Product 1

HCID 22616246HCID 22616246, compound

Procedure

N-(4-Iodo-5-methyl-3-isoxazolyl)benzenesulfonamide was prepared from 3-amino-4-iodo-5-methylisoxazole and benzenesulfonyl chloride according to the procedures described in Example 2b. The crude product was purified by recrystalization from ethyl acetate/hexanes to give a brown powder m.p. 138°-141° C., yield 46%.

Workup

  1. customThe crude product was purified by recrystalization from ethyl acetate/hexanes

Sources & evidence

ORD record
ord-387e05f6b6f64b6d88a63151b77fafce
Source dataset
uspto-grants-1996_05
Patent number
US05514691

Reaction notes

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