HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 439480Generated: October 30, 2026
Stannous Chloride → 8-Amino-5-chloro-7-Trifluoromethyl-1,4-dihydroquinoxaline-2,3-dione
https://huagongshe.com/reaction/439480
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Stannous Chloride | HCID 24479 | — |
| Reactant | 5-Chloro-8-nitro-7-trifluoromethyl-1,4-dihydroquinoxaline-2,3-dione | HCID 10686343 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 8-Amino-5-chloro-7-Trifluoromethyl-1,4-dihydroquinoxaline-2,3-dione | HCID 10802656 | 93.9% |
Reaction Steps
A mixture of 5-chloro-8-nitro-7-trifluoromethyl-1,4-dihydroquinoxaline-2,3-dione (25 mg, 0.08 mmol), SnCl2 ·2H2O (97 mg, 0.34 mmol) and EtOH (3 mL) was heated at 75° C. with stirring for 12 h. Work-up as above gave 21 mg (93%) of the title compound as a yellow powder. Mp>360° C. 1H NMR (DMSO-d6) 11.441 (s, 1H), 11.324 (s, 1H), 7.241 (s, 1H), 5.916 (s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05514680 |
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| Source dataset | uspto-grants-1996_05 |
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| ORD ID | ord-e0dbc3f01e4f402ca569eb2d8d4c9d8f |
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| Source note | uspto-grants-1996_05 |
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