HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromovanillin → N-(3-chlorophenyl)-2-cyano-3-(3-bromo-4-hydroxy-5-methoxyphenyl) propenamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromovanillin | HCID 18099 | — |
| Reactant | N-(3-chlorophenyl)-2-cyanoacetamide | HCID 679494 | — |
| Product | N-(3-chlorophenyl)-2-cyano-3-(3-bromo-4-hydroxy-5-methoxyphenyl) propenamide | HCID 53730904 | 65% |
Reaction Steps
The reaction was performed in the same manner as in Example 1 with 5-bromovanillin (1.38 g, 5.97 mmol) and N-(3-chlorophenyl) cyanoacetamide (1.16 g, 5.97 mmol) to give the objective N-(3-chlorophenyl)-2-cyano-3-(3-bromo-4-hydroxy-5-methoxyphenyl) propenamide (1.58 g, 65% in yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05514711 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-4408703937e1495ea883d675cacea422 |
| Source note | uspto-grants-1996_05 |