Chlorosuccinimide → HCID 15338149, compound

Participants

Reaction Steps

1.10 Grams (8.3 mmol) of the N-chlorosuccinimide was added little by little to a solution consisting of 2.15 g (7.6 mmol) of a 2-undecyl-4,5-bis(hydroxymethyl) imidazole and 200 ml of ethanol at a temperature of 40° to 45° C. over a period of about 23 minutes. The mixture was stirred at the same temperature for two hours to effect the reaction and, then, ethanol was distilled off under reduced pressure. The resulting reaction product was washed with water and was then recrystallized from acetone to obtain a creamy-white fine crystalline 2-undecyl-4-chloro-5-(hydroxymethyl) imidazole in an amount of 1.16 g (yield, 53.1%). By using acetonitrile, furthermore, the recrystallization was effected twice to obtain a colorless crystalline product in pure form. The TLC and spectra of this compound were the same as the properties exhibited the above-mentioned 2-undecyl-4-chloro-5-(hydroxymethyl) imidazole.

Provenance & Evidence