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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 43963Generated: October 29, 2026

Methanol → HCID 86648845, compound

https://huagongshe.com/reaction/43963

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantMethyl cis(+/-)-3-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-5-methoxybenzoateHCID 86648844—
CatalystHCID 178418390HCID 178418390—
SolventEthyl AcetateHCID 8857—
ProductHCID 86648845HCID 86648845—

Reaction Steps

The same operation as in Example (40e) was performed using methyl cis(±)-3-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-5-methoxybenzoate obtained in Example (257b) (106 mg, 0.25 mmol), a 10% palladium-carbon catalyst (42 mg), methanol (2 mL) and ethyl acetate (2 mL), to obtain the title compound. The resulting compound was used for the next reaction without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536197B2
Source datasetuspto-grants-2013_09
ORD IDord-b1c0dda8fbf242aba0ea2f59675c1d3b
Source noteuspto-grants-2013_09