tert-Butyl mercaptan → HCID 11106642, compound

Participants

Reaction Steps

A mixture of 4-methoxybenzyl alcohol (10.13 g) and zinc iodide (11.7 g) in 1,2-dichloroethane (120 mL) was treated with 2-methyl-2-propanethiol (9.92 mL) in one portion. The resulting mixture was stirred at room temperature. After about 18 hours, the reaction was diluted with water (100 mL) and methylene chloride (100 mL). The organic phase was removed, dried over magnesium sulfate, filtered, and concentrated in vacuo to give 14.4 g of an oil. 1H NMR (CDCl3): δ7.28 (d, 2H), 6.85 (d, 2H) , 3.77 (s, 3H), 3.73 (s, 2H), 1.36 (s, 9H). 13C NMR (CDCl3): δ130, 114, 56, 35, 32.

Provenance & Evidence