Methanol → Methyl cis(+/-)-5-(4-amino-3-methoxypiperidin-1-yl)-2-methoxybenzoate

Participants

Reaction Steps

The same operation as in Example (40e) was performed using methyl cis(±)-5-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-2-methoxybenzoate obtained in Example (258a) (35 mg, 0.08 mmol), a 10% palladium-carbon catalyst (9 mg), methanol (1.5 mL) and ethyl acetate (1.5 mL), to obtain the title compound. The resulting compound was used for the next reaction without purification.

Provenance & Evidence