Benzyl Chloride → HCID 22372525, compound

Participants

Reaction Steps

A solution of 33.55 g (100 mmol) of 3-dimethylaminopropyl 3,5-di-tert-butyl-4-hydroxybenzoate prepared as described above and 12.66 g (100 mmol) of benzyl chloride in 140 ml of acetonitrile was heated at reflux for 1 hour and 15 minutes and then concentrated under vacuum to a clear, thick oil. The resultant oil was allowed to stand overnight and crystallized. The solid was washed with ether, collected and dried giving 45.2 g (97.8% of theory) of N-[3-(3,5-di-tert-butyl-4-hydroxybenzoyloxy)propyl]-N,N-dimethylbenzylammonium chloride.

Provenance & Evidence