Methyl p-toluenesulfonate → HCID 21903207, compound

Participants

Reaction Steps

A mixture of 16.78 g (50 mmol) of 3-dimethylaminopropyl 3,5-di-tert-butyl-4-hydroxybenzoate, prepared as described in Example 4, 9.31 g (50 mmol) of methyl p-toluenesulfonate and 125 ml of acetonitrile was heated at reflux for 1 hour and 15 minutes and cooled. The collected solid was recrystallized from 140 ml of acetonitrile to give 19.48 g (74.7% of theory) of N-[3-(3,5-di-tert-butyl-4-hydroxybenzoyloxy)propyl)]trimethyl ammonium tosylate.

Provenance & Evidence