HCID 22402938, compound → HCID 54173576, compound

HRID 439709Notes

Reaction equation

HRID 439709 reaction equation
[CH3:1][N:2]1[C:6]2=[CH:7][CH:8]=[C:9]([C:14]([OH:16])=[O:15])[C:10]([C:11](O)=[O:12])=[C:5]2[N:4]=[C:3]1[CH3:17]>C(OC(=O)C)(=O)C>[CH3:1][N:2]1[C:6]2=[CH:7][CH:8]=[C:9]3[C:14](=[O:16])[O:15][C:11](=[O:12])[C:10]3=[C:5]2[N:4]=[C:3]1[CH3:17]

Participants

3

Reactant 1

HCID 22402938HCID 22402938, compound

Product 1

HCID 54173576HCID 54173576, compoundYield 89.9%

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

A mixture of 1,2-dimethyl-4,5-benzimidazoledicarboxylic acid (1.00 g, 4.27 mmol) and acetic anhydride (10 mL) is stirred 4 hours at reflux temperature, allowed to stand overnight at room temperature and filtered to afford the title product as yellow crystals (0.830 g, 89.8%), mp 295° C. (dec).

Workup

  1. temperatureat reflux temperature
  2. waitto stand overnight at room temperature
  3. filtrationfiltered

Sources & evidence

ORD record
ord-e42a841059ea4f3095fa968f5837777a
Source dataset
uspto-grants-1996_05
Patent number
US05516751

Reaction notes

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