Dicyclohexylcarbodiimide → HCID 67735793, compound

Participants

Reaction Steps

A mixture of 4-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-1,2-dimethyl-5-benzimidazolecarboxylic acid (0,942 g, 2.87 mmol), dicyclohexylcarbodiimide (0,590 g, 2.87 mmol) and tetrahydrofuran is stirred for 3 hours at reflux temperature, cooled and concentrated in vacuo. The residue is chromatographed (silica gel, ethyl acetate eluent) to afford the title product as a white powder (0.210 g, 23.6%), mp 258°-263° C.

Provenance & Evidence