HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-heptylacetamide → 1-Heptanamine, N-ethyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-heptylacetamide | HCID 347488 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | Sodium hydroxide--water (1/1/1) | HCID 23719242 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-Heptanamine, N-ethyl- | HCID 48038 | — |
Reaction Steps
A mixture of a solution of 5.5 gms of the N-heptylacetamide in 150 ml of diethyl ether and 3.99 gms of lithium aluminum hydride are stirred at room temperature for 18 hours. The reaction mixture is then worked up with H2O/NaOH by the Fieser method, following which the organic layer is dried over MgSO4, filtered, and concentrated under vacuum to give N-heptyl-N-ethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05516767 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-f49d0bbef8994d8586fdec05440b8c94 |
| Source note | uspto-grants-1996_05 |