HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Hydroxyphthalimide → 167081-33-6
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Hydroxyphthalimide | HCID 10665 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | ethyl N-ethoxycarbonyliminocarbamate | HCID 220568 | — |
| Reactant | 1,1-Dimethylethyl N-[3-(hydroxymethyl)cyclobutyl]carbamate | HCID 22408683 | — |
| Product | 167081-33-6 | HCID 22408678 | — |
Reaction Steps
Analogously to Example 6a, starting from 1.59 g (0.0079 mol) of 3-(N-BOC-amino)-cyclobutanemethanol (EP 0 366 059 A2), 1.29 g (0.0079 mol) of N-hydroxyphthalimide, 2.07 g (0.0079 mol) of triphenylphosphine and 1.39 ml (0.0083 mol) of diethyl azodicarboxylate (93%), the title compound is obtained, m.p. 108°-109° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05516806 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-3b74991f3714412da14ef4283832a981 |
| Source note | uspto-grants-1996_05 |