2-(Trifluoromethyl)benzoic acid → 2-(Trifluoromethyl)benzoyl chloride

Participants

Reaction Steps

A solution of 2.0 g of o-trifluoromethylbenzoic acid in 21 ml of thionyl chloride is heated at reflux for 1 hour. The volatiles are evaporated in vacuo to give a residue which is concentrated from toluene three times and dried under vacuum to give 2.1 g of the desired product as a residue.

Provenance & Evidence