HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → 4,5-Dihydro-5-(4-aminobenzoyl)pyrrolo[1,2-a]quinoxaline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 4,5-Dihydro-5-(4-nitrobenzoyl)pyrrolo[1,2-a]quinoxaline | HCID 21837135 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4,5-Dihydro-5-(4-aminobenzoyl)pyrrolo[1,2-a]quinoxaline | HCID 21837005 | — |
Reaction Steps
A mixture of 1 mmol of 4,5-dihydro-5-(4-nitrobenzoyl)pyrrolo[1,2-a]quinoxaline in 10 ml of ethyl alcohol and 10 ml of ethyl acetate containing 0.2 g of 10% Pd/C is hydrogenated for 5 hours. The reaction mixture is filtered through a pad of diatomaceous earth. The filtrate is concentrated in vacuo to a solid which is purified by flash chromatography to give the desired product, m.p. 225°-228° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05516774 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-b70ed097f33e4358bb3adf6a67d02155 |
| Source note | uspto-grants-1996_05 |