HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-Fluoro-2-methylbenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Fluoro-2-methylbenzoic acid | HCID 246682 | — |
| Product | 3-Fluoro-2-methylbenzoyl chloride | HCID 2779240 | — |
Reaction Steps
A solution of 2.87 g of 3-fluoro-2-methyl-benzoic acid in 25 ml of thionyl chloride is refluxed for 1.75 hour and the excess thionyl chloride removed under vacuum. To the residue is added toluene (several times) and the toluene removed under vacuum after each addition to give 3-fluoro-2-methylbenzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05516774 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-66e32ac8555e4fceb847454d9cffb1fd |
| Source note | uspto-grants-1996_05 |