HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Bromomethyl)-1-methylquinolin-2(1H)-one → 3-Ethyl-3-[3-(1-methyl-2-oxo-1,2-dihydroquinolin-6-ylmethoxy)phenyl]pentan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(Bromomethyl)-1-methylquinolin-2(1H)-one | HCID 15199065 | — |
| Reactant | 3-Ethyl-3-(3-hydroxyphenyl)pentan-2-one | HCID 22406589 | — |
| Product | 3-Ethyl-3-[3-(1-methyl-2-oxo-1,2-dihydroquinolin-6-ylmethoxy)phenyl]pentan-2-one | HCID 57321248 | 40% |
Reaction Steps
Using an analogous procedure to that described in Example 1, 6-bromomethyl-1-methyl-1,2-dihydroquinolin-2-one was reacted with 3-ethyl-3-(3-hydroxyphenyl)pentan-2-one to give 3-ethyl-3-[3-(1-methyl-2-oxo-1,2-dihydroquinolin-6-ylmethoxy)phenyl]pentan-2-one in 40% yield as a gum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05519022 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-fc8db2a832d24dd99ab2a2f6936a2575 |
| Source note | uspto-grants-1996_05 |