HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 22406556, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | HCID 22406568 | HCID 22406568 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 22406556 | HCID 22406556 | 55% |
Reaction Steps
Allyl 2-nitro-4-thiophenecarboxylate was suspended in concentrated HCl (25 ml), at 0°. SnCl2.2H2O (7.44 g, 32.36 mmol) was added and after stirring for 4 hours at ambient temperature the pH was adjusted to 10 with NaOH. Extraction with ethyl acetate and purification by subjecting to flash silica gel chromatography using ethyl acetate/petroleum ether as eluant (25:75), gave the title compound (1.15 g, 55%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05519015 |
| Source dataset | uspto-grants-1996_05 |
| ORD ID | ord-3d1d6fa1850b44748b5f2552211d6e87 |
| Source note | uspto-grants-1996_05 |