HCID 22406961, compound → HCID 22406929, compound

Participants

Reaction Steps

2-(1-hexynyl)-5-thiazole sulfonamide (0.04 g, 0.16 mmol) was dissolved in 5 mL of methanol. 0.01 g of palladium/carbon was added and the solution purged three times with hydrogen. The reaction was left under 30 psi of hydrogen for 48 hours. The mixture was filtered through celite and the filtrate concentrated. The residue was purified on the chromatatron (eluted with 5:1.5:3.5 CH2Cl2 /Et2O, hexane) to afford 32 mg (80%) of 2-hexyl-5-thiazole sulfonamide.

Provenance & Evidence