Maleic Acid → HCID 86749494, compound

Participants

Reaction Conditions

Reaction Steps

A solution of maleic acid (0.030 g) in absolute ethanol (0.4 mL) is added drop-wise into a stirred solution of 2-[2-(dimethylamino) ethyl]-5-[[2-(amino) ethyl]amino]isoquino[8,7,6-cd]indazole-6(2H)-one of Example 12 (0.030 g) in absolute ethanol (1.5 ml) held at 50° C. After the addition is complete the reaction mixture is maintained at 50° C. for 3 minutes and then allowed to cool to room temperature. After one hour the red-amaranth crystalline material which separated is filtered, washed with ethanol and dried under vacuum at 40° C. to give 2-[2-(dimethylamino)ethyl]-5-[[2-(amino)ethyl]amino]isoquino [8,7,6-cd]indazole-6(2H)-one dimaleate (0.029 g).

Provenance & Evidence