5-Hydroxy-1,3-dimethyl-1,3-dihydro-2H-indol-2-one → HCID 10867765, compound

HRID 440449Notes

Reaction equation

HRID 440449 reaction equation
[CH3:1][CH2:2][O:3]C1C=CC2N(C)[C@H]3N(C)CC[C@@]3(C)C=2C=1.[CH3:19][N:20]1[C:28]2[C:23](=[CH:24][C:25]([OH:29])=[CH:26][CH:27]=2)[CH:22]([CH3:30])[C:21]1=[O:31]>>[CH3:19][N:20]1[C:28]2[C:23](=[CH:24][C:25]([O:29][C:2](=[O:3])[CH3:1])=[CH:26][CH:27]=2)[CH:22]([CH3:30])[C:21]1=[O:31]

Participants

3

Reactant 2

HCID 6008945-Hydroxy-1,3-dimethyl-1,3-dihydro-2H-indol-2-one2×HCID 10879418Eserethole

Product 1

HCID 10867765HCID 10867765, compound

Procedure

A process for the preparation of eserethole of formula ##STR7## which comprises the steps of: a) acylating the compound II 1,3-dimethyl-5-hydroxy-oxindole to obtain 1,3-dimethyl-5-acyloxy-oxindole (III);

Sources & evidence

ORD record
ord-6519baf32e8a48b6ba98e31a3f5798ee
Source dataset
uspto-grants-1996_05
Patent number
US05519144

Reaction notes

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