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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 440544Generated: November 1, 2026

Ammonia → 2-(Oxetan-3-oxycarbonyl)phenylsulfonamide

https://huagongshe.com/reaction/440544

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantDichloromethaneHCID 6344—
Reactant2-(Oxetan-3-oxycarbonyl)phenylsulfonyl chlorideHCID 23353118—
SolventWaterHCID 962—
Product2-(Oxetan-3-oxycarbonyl)phenylsulfonamideHCID 23353117—

Reaction Steps

##STR18## 2.5 g of ammonia are passed into a methylene chloride solution of 2-(oxetan-3-oxycarbonyl)phenylsulfonyl chloride (Example H6) at a temperature of 0° to 5° C. in the course of 45 minutes. By adding water to the reaction mixture, washing the organic phase with water, drying and evaporating it and crystallising the residue from a methylene chloride/diethyl ether mixture, 6.7 g of 2-(oxetan-3-oxycarbonyl)phenylsulfonamide of melting point 169° to 170° C. are obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05519148
Source datasetuspto-grants-1996_05
ORD IDord-c2f33ace0be5460bb0f814c383aab862
Source noteuspto-grants-1996_05